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HHV, which stands for Human Herpesvirus, refers to a group of viruses that infect humans. There are eight known types of HHV, which include HHV-1 (also known as herpes simplex virus 1 or HSV-1), HHV-2 (herpes simplex virus 2 or HSV-2), HHV-3 (varicella-zoster virus or VZV), HHV-4 (Epstein-Barr virus or EBV), HHV-5 (cytomegalovirus or CMV), HHV-6A and 6B, HHV-7, and HHV-8 (Kaposi's sarcoma-associated herpesvirus or KSHV).These viruses can cause various diseases in humans. For example, HSV-1 and HSV-2 can cause oral and genital herpes respectively. VZV causes chickenpox during the primary infection and shingles during reactivation. EBV is associated with infectious mononucleosis and is also linked to certain types of cancer such as Burkitt's lymphoma and nasopharyngeal carcinoma.CMV affects people of all ages but usually causes mild symptoms in healthy individuals. However, it can lead to severe complications in immunocompromised individuals such as those with HIV/AIDS or undergoing organ transplantation.HHV-6A and 6B are common childhood infections that cause roseola infantum (also known as sixth disease). They can also lead to complications in transplant recipients.HHV-7 is closely related to HHV-6A and 6B but is less well-studied. It has been associated with several illnesses including exanthem subitum (a rash illness in infants) and neurological disorders.KSHV is primarily associated with Kaposi's sarcoma, a type of cancer that commonly affects individuals with weakened immune systems such as those with HIV/AIDS.HHV infections typically persist for life, with the viruses remaining latent (dormant) in the body and reactivating under certain conditions. These viruses are usually transmitted through direct contact with infected individuals or via respiratory droplets, sexual contact, or vertical transmission from mother to child during childbirth.Treatment options for HHV infections vary depending on the specific virus and disease. Antiviral medications are commonly used to manage symptoms and reduce viral replication. Vaccines are available for some HHV types, such as VZV (chickenpox vaccine) and HSV

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